PIGK Antibody

Datasheet

Code	CSB-PA842143LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate All lanes: PIGK antibody at 2.5µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 46, 37 kDa Observed band size: 46 kDa Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA842143LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PIGK Polyclonal antibody

Uniprot No.

Q92643

Target Names

PIGK

Alternative Names

PIGK antibody; GPI8 antibody; GPI-anchor transamidase antibody; GPI transamidase antibody; EC 3.-.-.- antibody; GPI8 homolog antibody; hGPI8 antibody; Phosphatidylinositol-glycan biosynthesis class K protein antibody; PIG-K antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human GPI-anchor transamidase protein (91-293AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PIGK Antibody (Product code: CSB-PA842143LA01HU) is Non-conjugated. For PIGK Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA842143LB01HU	PIGK Antibody, HRP conjugated	ELISA
FITC	CSB-PA842143LC01HU	PIGK Antibody, FITC conjugated
Biotin	CSB-PA842143LD01HU	PIGK Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

Gene References into Functions

Report firstly demonstrated that inadequate protein-glycosylphosphatidylinositol anchoring caused by suppression of PIGK might affect the expression or function of some glycosylphosphatidylinositol-anchored proteins associated with tyrosinase activity. PMID: 27919619
Our results demonstrate, for the first time, a link between the SNP 1048575 and low PIGK expression in CRC/HCC patients and also suggest a possible association between altered PIGK expression and disease susceptibility. PMID: 22824918
GPI8 and PIG-T form a functionally important intermolecular disulfide bridge PMID: 12582175

Subcellular Location

Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Protein Families

Peptidase C13 family

Database Links

HGNC: 8965

OMIM: 605087

KEGG: hsa:10026

STRING: 9606.ENSP00000359848

UniGene: Hs.178305

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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