PIGR Antibody, HRP conjugated

Code CSB-PA017981LB01BO
Size US$166
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Product Details

Full Product Name
Rabbit anti-Bos taurus (Bovine) PIGR Polyclonal antibody
Uniprot No.
Target Names
PIGR
Alternative Names
PIGR antibody; Polymeric immunoglobulin receptor antibody; PIgR antibody; Poly-Ig receptor) [Cleaved into: Secretory component] antibody
Raised in
Rabbit
Species Reactivity
Bovine
Immunogen
Recombinant Bovine Polymeric immunoglobulin receptor protein (399-599AA)
Immunogen Species
Bos taurus (Bovine)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mediates selective transcytosis of polymeric IgA and IgM across mucosal epithelial cells. Binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.; Through its N-linked glycans ensures anchoring of secretory IgA (sIgA) molecules to mucus lining the epithelial surface to neutralize extracellular pathogens. On its own (free form) may act as a non-specific microbial scavenger to prevent pathogen interaction with epithelial cells.
Gene References into Functions
  1. This study evaluated the production of polymeric immunoglobulin receptor and immunoglobulin A in the salivary glands of cattle. PMID: 23395346
Subcellular Location
[Polymeric immunoglobulin receptor]: Cell membrane; Single-pass type I membrane protein.; [Secretory component]: Secreted.
Tissue Specificity
Found in mammary gland, jejunum, lung, kidney and small intestine.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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