PITPNA Antibody, FITC conjugated

Datasheet

Code	CSB-PA018035LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PITPNA Polyclonal antibody

Uniprot No.

Q00169

Target Names

PITPNA

Alternative Names

MGC99649 antibody; Phosphatidylinositol transfer protein alpha antibody; Phosphatidylinositol transfer protein alpha isoform antibody; Phosphotidylinositol transfer protein antibody; PI-TP-alpha antibody; PIPNA_HUMAN antibody; PITP alpha antibody; Pitpna antibody; PITPNB antibody; PtdIns transfer protein alpha antibody; PtdInsTP alpha antibody; PtdInsTP antibody; Vb antibody; VIB1A antibody; Vibrator antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Phosphatidylinositol transfer protein alpha isoform protein (1-270AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions. Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3.

Gene References into Functions

Data show that phosphatidylinositol transfer protein alpha (PITPalpha) is involved in the function of mixed lineage kinase domain-like protein (MLKL) in necroptosis. PMID: 29104146
the PITPalpha structure has to relax to allow access to the Ser166 site, and this may occur at the membrane surface where PI delivery is required for receptor-mediated PLC signaling PMID: 15322105
the apparent occurrence of an unusual TG 3' splice site in intron 4 is discussed PMID: 17672918

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

PtdIns transfer protein family, PI transfer class I subfamily

Database Links

HGNC: 9001

OMIM: 600174

KEGG: hsa:5306

STRING: 9606.ENSP00000316809

UniGene: Hs.429819

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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