PSG9 Antibody

Code CSB-PA27499A0Rb
Size US$166
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Image
  • IHC image of CSB-PA27499A0Rb diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • IHC image of CSB-PA27499A0Rb diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • Immunofluorescence staining of MCF-7 cells with CSB-PA27499A0Rb at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PSG9 Polyclonal antibody
Uniprot No.
Target Names
PSG9
Alternative Names
pregnancy specific beta 1 glycoprotein (PSG) antibody; pregnancy specific beta 1 glycoprotein 11 antibody; pregnancy specific beta 1 glycoprotein 9 antibody; pregnancy specific beta 1 glycoprotein B antibody; Pregnancy-specific beta-1 glycoprotein B antibody; Pregnancy-specific beta-1-glycoprotein 11 antibody; Pregnancy-specific beta-1-glycoprotein 9 antibody; Pregnancy-specific glycoprotein 11 antibody; Pregnancy-specific glycoprotein 7 antibody; Pregnancy-specific glycoprotein 9 antibody; PS beta B antibody; PS-beta-B antibody; PS-beta-G-11 antibody; PS-beta-G-9 antibody; PS34 antibody; PSBG 9 antibody; PSBG-11 antibody; PSBG-9 antibody; PSG 9 antibody; PSG11 antibody; PSG7 antibody; PSG9 antibody; PSG9_HUMAN antibody; PSGII antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Pregnancy-specific beta-1-glycoprotein 9 protein (241-426AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PSG9 Antibody (Product code: CSB-PA27499A0Rb) is Non-conjugated. For PSG9 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA27499B0Rb PSG9 Antibody, HRP conjugated ELISA
FITC CSB-PA27499C0Rb PSG9 Antibody, FITC conjugated
Biotin CSB-PA27499D0Rb PSG9 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Results indicate that pregnancy-specific glycoprotein 9 (PSG9) may facilitate the development of hepatocellular carcinoma (HCC) by fostering angiogenesis via promoting VEGFA production in cancer HCC. PMID: 28078509
  2. Findings illustrate the innovative mechanism by which PSG9 drives the progression of colorectal cancer and tumor angiogenesis. This occurs via nuclear translocation of PSG9/SMAD4, which activates angiogenic cytokines. PMID: 27528036
  3. PSG9, through its activation of TGFbeta-1, could be a potent inducer of immune tolerance PMID: 27389696
  4. PSG9 may have a role in development of colorectal carcinogenesis in patients with adenomatous polyposis coli PMID: 15982419
Subcellular Location
Secreted.
Protein Families
Immunoglobulin superfamily, CEA family
Database Links

HGNC: 9526

OMIM: 176398

KEGG: hsa:5678

STRING: 9606.ENSP00000270077

UniGene: Hs.502092

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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