PSG9 Antibody

Code CSB-PA27499A0Rb
Size US$166
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Image
  • IHC image of CSB-PA27499A0Rb diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • IHC image of CSB-PA27499A0Rb diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • Immunofluorescence staining of MCF-7 cells with CSB-PA27499A0Rb at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PSG9 Polyclonal antibody
Uniprot No.
Target Names
PSG9
Alternative Names
pregnancy specific beta 1 glycoprotein (PSG) antibody; pregnancy specific beta 1 glycoprotein 11 antibody; pregnancy specific beta 1 glycoprotein 9 antibody; pregnancy specific beta 1 glycoprotein B antibody; Pregnancy-specific beta-1 glycoprotein B antibody; Pregnancy-specific beta-1-glycoprotein 11 antibody; Pregnancy-specific beta-1-glycoprotein 9 antibody; Pregnancy-specific glycoprotein 11 antibody; Pregnancy-specific glycoprotein 7 antibody; Pregnancy-specific glycoprotein 9 antibody; PS beta B antibody; PS-beta-B antibody; PS-beta-G-11 antibody; PS-beta-G-9 antibody; PS34 antibody; PSBG 9 antibody; PSBG-11 antibody; PSBG-9 antibody; PSG 9 antibody; PSG11 antibody; PSG7 antibody; PSG9 antibody; PSG9_HUMAN antibody; PSGII antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Pregnancy-specific beta-1-glycoprotein 9 protein (241-426AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PSG9 Antibody (Product code: CSB-PA27499A0Rb) is Non-conjugated. For PSG9 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA27499B0Rb PSG9 Antibody, HRP conjugated ELISA
FITC CSB-PA27499C0Rb PSG9 Antibody, FITC conjugated
Biotin CSB-PA27499D0Rb PSG9 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Gene References into Functions
  1. Results indicate that pregnancy-specific glycoprotein 9 (PSG9) may facilitate the development of hepatocellular carcinoma (HCC) by fostering angiogenesis via promoting VEGFA production in cancer HCC. PMID: 28078509
  2. Findings illustrate the innovative mechanism by which PSG9 drives the progression of colorectal cancer and tumor angiogenesis. This occurs via nuclear translocation of PSG9/SMAD4, which activates angiogenic cytokines. PMID: 27528036
  3. PSG9, through its activation of TGFbeta-1, could be a potent inducer of immune tolerance PMID: 27389696
  4. PSG9 may have a role in development of colorectal carcinogenesis in patients with adenomatous polyposis coli PMID: 15982419
Subcellular Location
Secreted.
Protein Families
Immunoglobulin superfamily, CEA family
Database Links

HGNC: 9526

OMIM: 176398

KEGG: hsa:5678

STRING: 9606.ENSP00000270077

UniGene: Hs.502092

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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