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RASA2 Antibody, HRP conjugated

Datasheet
Code CSB-PA622992LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RASA2 Polyclonal antibody
Uniprot No.
Q15283
Target Names
RASA2
Alternative Names
GAP1m antibody; GTPase activating protein of RAS antibody; Ras GTPase activating protein 2 antibody; Ras GTPase-activating protein 2 antibody; RAS p21 protein activator 2 antibody; Rasa2 antibody; RASA2_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ras GTPase-activating protein 2 protein (609-850AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

RASA2 Antibodies

RASA2 Proteins

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Target Background

Function
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).
Gene References into Functions
  1. Recurrent inactivating RASA2 mutations are associated with melanoma. PMID: 26502337
  2. GAP1m is a Ras GAP that switches off Ras signalling. GAP1m undergoes a plasma membrane association following growth factor stimulation of PI 3-kinase as a result of its PH domain binding to phosphatidylinositol 3,4,5-trisphosphate. PMID: 10074452
Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region.
Database Links

HGNC: 9872

OMIM: 601589

KEGG: hsa:5922

STRING: 9606.ENSP00000286364

UniGene: Hs.655941

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Related pathways
MAPK signaling pathway Ras signaling pathway
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