RASA2 Antibody

Code CSB-PA622992LA01HU
Size US$166
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  • Immunofluorescence staining of U251 cells with CSB-PA622992LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RASA2 Polyclonal antibody
Uniprot No.
Target Names
RASA2
Alternative Names
GAP1m antibody; GTPase activating protein of RAS antibody; Ras GTPase activating protein 2 antibody; Ras GTPase-activating protein 2 antibody; RAS p21 protein activator 2 antibody; Rasa2 antibody; RASA2_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ras GTPase-activating protein 2 protein (609-850AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The RASA2 Antibody (Product code: CSB-PA622992LA01HU) is Non-conjugated. For RASA2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA622992LB01HU RASA2 Antibody, HRP conjugated ELISA
FITC CSB-PA622992LC01HU RASA2 Antibody, FITC conjugated
Biotin CSB-PA622992LD01HU RASA2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).
Gene References into Functions
  1. Recurrent inactivating RASA2 mutations are associated with melanoma. PMID: 26502337
  2. GAP1m is a Ras GAP that switches off Ras signalling. GAP1m undergoes a plasma membrane association following growth factor stimulation of PI 3-kinase as a result of its PH domain binding to phosphatidylinositol 3,4,5-trisphosphate. PMID: 10074452
Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region.
Database Links

HGNC: 9872

OMIM: 601589

KEGG: hsa:5922

STRING: 9606.ENSP00000286364

UniGene: Hs.655941

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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