RASAL2 Antibody

1. Furthermore, overexpression of miR-203 exhibited a similar effect to RASAL2 knockdown in hepatocellular carcinoma (HCC) cells. These results indicated that RASAL2 serves a tumor oncogenic role in HCC and may be considered a potential target in HCC. PMID: 28447723
2. Study shows that up to 62% of luminal B cancers have lost expression of at least one of the DAB2IP and RASAL2 genes. However, the tumors that have lost both genes frequently present as advanced disease and are more likely to recur. Importantly, the report provide evidence that DAB2IP and RASAL2 can individually function as tumor suppressors in breast cancer. PMID: 27974415
3. RASAL2 could inhibit BCa tumorigenesis. PMID: 28182001
4. these results demonstrated that miRNA-136 was a key anti-invasive miRNA and further confirmed the oncogenic role of RASAL2 in triple-negative breast cancer. PMID: 27108696
5. High RASAL2 expression is associated with liver cancer. PMID: 24763612
6. these results indicate that activation of a RASAL2/ARHGAP24/RAC1 module contributes to TNBC tumorigenesis and identify a context-dependent role of RASAL2 in breast cancer. PMID: 25384218
7. Results implicate RASAL2 as an EMT regulator and tumor suppressor in ovarian cancer, and down-regulation of RASAL2 promotes ovarian cancer progression. PMID: 25216515
8. the down-regulation of RASAL2 promotes metastatic progression of lung adenocarcinoma PMID: 25446096
9. The RasGAP gene, RASAL2, is a tumor and metastasis suppressor. PMID: 24029233
10. RASAL2 was identified as an ECT2-interacting protein that regulates RHO activity in astrocytoma cells. PMID: 22683310

Show More

Hide All

HGNC: 9874

OMIM: 606136

KEGG: hsa:9462

STRING: 9606.ENSP00000356621

UniGene: Hs.496139