RASSF3 Antibody, Biotin conjugated

Code CSB-PA801247LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RASSF3 Polyclonal antibody
Uniprot No.
Target Names
RASSF3
Alternative Names
MGC119194 antibody; MGC119195 antibody; MGC119197 antibody; Ras association (RalGDS/AF 6) domain family 3 antibody; Ras association domain containing protein 3 antibody; Ras association domain-containing protein 3 antibody; RASF3_HUMAN antibody; Rassf3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ras association domain-containing protein 3 protein (2-109AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Gene References into Functions
  1. low expression is associated with malignant phenotypes in non-small cell lung cancer patients PMID: 24246507
  2. Taken together, these findings indicate that the RASSF3 promoter rs6581580 T>G SNP is potentially functional, modulating susceptibility to SCCHN among non-Hispanic whites. PMID: 24295637
  3. hypermethylation-induced RASSF3 silencing plays an important role in the tumorigenesis of pituitary somatotroph adenomas. PMID: 23555615
  4. tumor suppressor activity of RASSF3, which occurs through p53 stabilization and regulation of apoptosis and the cell cycle. PMID: 22593196
  5. Observational study of gene-disease association. (HuGE Navigator) PMID: 20237496
  6. Mammary tumor incidence in bi-transgenic mice is delayed, suggesting that transgenic Rassf3 may influence mammary tumor incidence in transgenic mice PMID: 19148488
  7. The presence of a Ras association domain common to NORE1,RASSF1, and RASSF3 suggests their possible involvement inRas-like signaling pathways. PMID: 11965544

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Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Note=Localized to microtubules in vascular endothelial cells.
Tissue Specificity
Widely expressed.
Database Links

HGNC: 14271

OMIM: 607019

KEGG: hsa:283349

STRING: 9606.ENSP00000336616

UniGene: Hs.643605

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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