RASSF3 Antibody, FITC conjugated

Code CSB-PA801247LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RASSF3 Polyclonal antibody
Uniprot No.
Target Names
RASSF3
Alternative Names
MGC119194 antibody; MGC119195 antibody; MGC119197 antibody; Ras association (RalGDS/AF 6) domain family 3 antibody; Ras association domain containing protein 3 antibody; Ras association domain-containing protein 3 antibody; RASF3_HUMAN antibody; Rassf3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ras association domain-containing protein 3 protein (2-109AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. low expression is associated with malignant phenotypes in non-small cell lung cancer patients PMID: 24246507
  2. Taken together, these findings indicate that the RASSF3 promoter rs6581580 T>G SNP is potentially functional, modulating susceptibility to SCCHN among non-Hispanic whites. PMID: 24295637
  3. hypermethylation-induced RASSF3 silencing plays an important role in the tumorigenesis of pituitary somatotroph adenomas. PMID: 23555615
  4. tumor suppressor activity of RASSF3, which occurs through p53 stabilization and regulation of apoptosis and the cell cycle. PMID: 22593196
  5. Observational study of gene-disease association. (HuGE Navigator) PMID: 20237496
  6. Mammary tumor incidence in bi-transgenic mice is delayed, suggesting that transgenic Rassf3 may influence mammary tumor incidence in transgenic mice PMID: 19148488
  7. The presence of a Ras association domain common to NORE1,RASSF1, and RASSF3 suggests their possible involvement inRas-like signaling pathways. PMID: 11965544

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Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Note=Localized to microtubules in vascular endothelial cells.
Tissue Specificity
Widely expressed.
Database Links

HGNC: 14271

OMIM: 607019

KEGG: hsa:283349

STRING: 9606.ENSP00000336616

UniGene: Hs.643605

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