RBL1 Antibody, Biotin conjugated

Datasheet
Code CSB-PA019398LD01HU
Size US$299

Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) RBL1 Polyclonal antibody
Uniprot No. P28749
Target Names RBL1
Alternative Names Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1), RBL1
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Retinoblastoma-like protein 1 protein (201-500AA)
Immunogen Species Homo sapiens (Human)
Conjugate Biotin
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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Target Data

Function Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.
Subcellular Location Nucleus
Protein Families Retinoblastoma protein (RB) family
Database Links

HGNC: 9893

OMIM: 116957

KEGG: hsa:5933

STRING: 9606.ENSP00000362768

UniGene: Hs.207745

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