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RBP2 Antibody

Datasheet
Code CSB-PA019481DSR1HU
Size US$166
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Image
  • Western Blotting(WB) - RBP2 Antibody

    Western blot
    All lanes: RBP2antibody at 1.76μg/ml
    Lane 1: Hela whole cell lysate
    Lane 2: HepG2 whole cell lysate
    Lane 3: Jurkat whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 192 kDa
    Observed band size: 192 kDa

  • Immunohistochemistry(IHC) 1- RBP2 Antibody

    Immunohistochemistry of paraffin-embedded human duodenal tissue using CSB-PA019481DSR1HU at dilution of 1:100

  • Immunohistochemistry(IHC) 2- RBP2 Antibody

    Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA019481DSR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RBP2 Polyclonal antibody
Uniprot No.
P50120
Target Names
RBP2
Alternative Names
Cellular retinol binding protein II antibody; Cellular retinol-binding protein II antibody; CRABP II antibody; Crbp 2 antibody; CRBP II antibody; CRBP-II antibody; CRBP2 antibody; CrbpII antibody; MGC159254 antibody; MGC159256 antibody; Rbp 2 antibody; Rbp2 antibody; RBPC2 antibody; RET2_HUMAN antibody; Retinol binding protein 2 antibody; Retinol binding protein 2 cellular antibody; Retinol-binding protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Retinol-binding protein 2 protein (1-134AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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RBP2 Antibodies

RBP2 Proteins

Customer Reviews and Q&A

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Target Background

Function
Intracellular transport of retinol.
Gene References into Functions
  1. study demonstrates that Piasy may prevent exaggerated transcription of IFNI by Rbp2-mediated demethylation of H3K4me3 of IFNI, avoiding excessive immune responses PMID: 28970247
  2. Domain-swapped dimers of RBP2 provides evidence for ordered folding intermediates. PMID: 27524203
  3. The structure of retinal-bound human CRBPII and the structure of retinol-bound CRBPII with retinol fully occupying the binding pocket are reported. PMID: 25478840
  4. With only nine point mutations, the hCRBPII mutants induced a systematic shift in the absorption profile of all-trans-retinal of more than 200 nanometers across the visible spectrum. PMID: 23224553
  5. retinoic acid responsiveness of the human CRBP II promoter is mediated by an indirect mechanism and that this mechanism is associated with enterocyte differentiation. PMID: 12016134
  6. We report here the X-ray structures of human apo and holo CRBP II solved at 1.2 A resolution and compare the two structures between them and with the structures of zebrafish and rat CRBP II. PMID: 18076076
  7. HNF-4alpha is an important transcriptional factor that regulates human CRBPII gene expression; possibility for a novel function of HNF-4alpha in the regulation of human intestinal vitamin A absorption and metabolism PMID: 19147806

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Subcellular Location
Cytoplasm.
Protein Families
Calycin superfamily, Fatty-acid binding protein (FABP) family
Tissue Specificity
Higher expression in adult small intestine and to a much lesser extent in fetal kidney.
Database Links

HGNC: 9920

OMIM: 180280

KEGG: hsa:5948

STRING: 9606.ENSP00000232217

UniGene: Hs.655516

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