RDH11 Antibody

Datasheet

Code	CSB-PA903114
Size	US$166
	Order now
Image	The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA903114(RDH11 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q8TC12

Target Names

RDH11

Alternative Names

Androgen regulated short chain dehydrogenase/reductase 1 antibody; Androgen-regulated short-chain dehydrogenase/reductase 1 antibody; ARSDR1 antibody; AU045252 antibody; C85936 antibody; CGI 82 antibody; FLJ32633 antibody; HCBP12 antibody; HCV core binding protein antibody; HCV core binding protein HCBP12 antibody; HCV core-binding protein HCBP12 antibody; MDT1 antibody; Prostate short chain dehydrogenase/reductase 1 antibody; Prostate short-chain dehydrogenase/reductase 1 antibody; PSDR1 antibody; RALR1 antibody; RDH11 antibody; RDH11_HUMAN antibody; Retinal reductase 1 antibody; retinol dehydrogenase 11 (all trans/9 cis/11 cis) antibody; Retinol dehydrogenase 11 antibody; SCALD antibody; SDR7C1 antibody; Short chain dehydrogenase/reductase family 7C; member 1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Fusion protein of Human RDH11

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:10-1:50

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol. Exhibits a low reductive activity towards unsaturated medium-chain aldehydes such as cis -6-nonenal and no activity toward nonanal or 4-hydroxy-nonenal. Has no dehydrogenase activity towards steroid.

Gene References into Functions

Data suggest that membrane anchoring of retinol dehydrogenase 11 (RDH11) is likely driven by its N-terminal segment. PMID: 25542782
Data indicate that ribosomal protein L11 (RPL11)-expressing cells proliferated more rapidly than the ribosomal protein L11 (RPL11)-expressing cells. PMID: 25829192
deleterious mutations in RDH11, an important enzyme for vision-related and systemic retinoic acid metabolism, cause a new syndrome with RP. PMID: 24916380
Prostate short-chain dehydrogenase/reductase (PSDR1) encodes a novel retinal reductase (RalR1). PMID: 12036956
The core protein of HCV can interact with translin protein. This can partly explain the molecular mechanism for hepatocellular carcinoma and lymphoma caused by HCV. PMID: 12532453
Expression pattern and high catalytic efficiency of RalR1 are consistent with the hypothesis that RalR1 contributes to the reduction of retinal in various human tissues. PMID: 14674758
RDH11 localizes to photoreceptor inner segments [review] PMID: 17249616

Hide All

Involvement in disease

Retinal dystrophy, juvenile cataracts, and short stature syndrome (RDJCSS)

Subcellular Location

Endoplasmic reticulum membrane; Single-pass type II membrane protein.

Protein Families

Short-chain dehydrogenases/reductases (SDR) family

Tissue Specificity

Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and f

Database Links

HGNC: 17964

OMIM: 607849

KEGG: hsa:51109

STRING: 9606.ENSP00000370750

UniGene: Hs.719925

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address