RHOF Antibody, HRP conjugated

Datasheet

Code	CSB-PA867192LB01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RHOF Polyclonal antibody

Uniprot No.

Q9HBH0

Target Names

RHOF

Alternative Names

ARHF antibody; FLJ20247 antibody; Ras homolog gene family member F (in filopodia) antibody; Ras homolog gene family member F antibody; Rho F antibody; Rho family GTPase Rif antibody; Rho in filopodia antibody; Rho related GTP binding protein RhoF antibody; Rho-related GTP-binding protein RhoF antibody; Rhof antibody; RHOF_HUMAN antibody; RIF antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Rho-related GTP-binding protein RhoF protein (1-170AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology.

Gene References into Functions

Rif has two separate roles in FARP1 regulation-in controlling its association with plexinA4, and in releasing active RhoA from a plexinA4/FARP1 complex. PMID: 25668492
In the present review, our aim is to summarize the current information about the Rif effectors and how Rif remodels actin cytoskeleton in many aspects. [Review] PMID: 22260703
The authors show that enteropathogenic Escherichia coli translocates EspH, which inactivates mammalian RhoGEFs and triggers cytotoxicity. PMID: 22251971
Rif GTPase is an alternative trigger of stress-fiber formation in epithelial cells. PMID: 20233848
deletion of genes RHOF in early-stage mycosis fungoides. PMID: 18663754
The protein encoded by this gene causes the formation of long, actin-rich filopodia. In combination with RAC1 and CDC42 it causes additional actin rearrangments, suggesting that this protein is intimately involved in regulation of the cytoskeleton. PMID: 11084341

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Subcellular Location

Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton.

Protein Families

Small GTPase superfamily, Rho family

Database Links

HGNC: 15703

KEGG: hsa:54509

STRING: 9606.ENSP00000267205

UniGene: Hs.707579

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Related pathways

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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