RORB Antibody

Datasheet

Code	CSB-PA821694LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: U87 whole cell lysate All lanes: RORB antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 54, 53 kDa Observed band size: 54 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RORB Polyclonal antibody

Uniprot No.

Q92753

Target Names

RORB

Alternative Names

bA133M9.1 antibody; NR1F2 antibody; Nuclear receptor ROR-beta antibody; Nuclear receptor RZR beta antibody; Nuclear receptor RZR-beta antibody; Nuclear receptor subfamily 1 group F member 2 antibody; OTTHUMP00000021486 antibody; RAR related orphan receptor B antibody; RAR related orphan receptor beta antibody; Retinoic acid binding receptor beta antibody; Retinoid-related orphan receptor-beta antibody; ROR BETA antibody; Rorb antibody; RORB_HUMAN antibody; RZR BETA antibody; RZRB antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Nuclear receptor ROR-beta protein (1-269AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The RORB Antibody (Product code: CSB-PA821694LA01HU) is Non-conjugated. For RORB Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA821694LB01HU	RORB Antibody, HRP conjugated	ELISA
FITC	CSB-PA821694LC01HU	RORB Antibody, FITC conjugated
Biotin	CSB-PA821694LD01HU	RORB Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity.; Isoform 1 is critical for hindlimb motor control and for the differentiation of amacrine and horizontal cells in the retina. Regulates the expression of PTF1A synergistically with FOXN4.

Subcellular Location

Nucleus, nucleoplasm.

Protein Families

Nuclear hormone receptor family, NR1 subfamily

Database Links

HGNC: 10259

OMIM: 601972

STRING: 9606.ENSP00000366093

UniGene: Hs.494178

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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