Code | CSB-PA624103LA01HU |
Size | US$166 |
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The RPE65 Antibody (Product code: CSB-PA624103LA01HU) is Non-conjugated. For RPE65 Antibody with conjugates, please check the following table.
Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IF | 1:200-1:500 |
The RPE65 polyclonal antibody is obtained from rabbits with the recombinant human RPE65 protein (348-484aa) immunized. It is specific for human and rat RPE65 proteins. This RPE65 antibody underwent protein G affinity and got at least 95% purity. The RPE65 antibody was validated for use in ELISA, WB, and IF applications.
The RPE65 protein mainly acts as an isomerohydrolase enzyme that catalyzes the isomerization of all-trans retinyl esters to 11-cis retinol, a key step in the visual cycle essential for vision. Mutations in the RPE65 gene can result in a range of inherited retinal diseases, including Leber congenital amaurosis (LCA) and retinitis pigmentosa (RP).
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