RPS27 Antibody

Code CSB-PA020419ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA020419ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RPS27 Polyclonal antibody
Uniprot No.
Target Names
RPS27
Alternative Names
2610206D02Rik antibody; 3200001M24Rik antibody; 40S ribosomal protein S27 antibody; C530005D02Rik antibody; Metallopan stimulin 1 antibody; Metallopan-stimulin 1 antibody; Metallopanstimulin 1 antibody; Metallopanstimulin1 antibody; MPS 1 antibody; MPS-1 antibody; MPS1 antibody; pmn antibody; Ribosomal protein S27 antibody; Ribosomal protein S27 metallopanstimulin 1 antibody; rps27 antibody; RS27_HUMAN antibody; S27 antibody; snoRNA MBI 112 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human 40S ribosomal protein S27 protein (1-84AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the small ribosomal subunit. Required for proper rRNA processing and maturation of 18S rRNAs.
Gene References into Functions
  1. Chloride anion behaves as a signaling effector for CFTR in the modulation of RPS27 expression. PMID: 28941802
  2. reveal how Mps1 dynamically modifies kinetochores to correct improper attachments and ensure faithful chromosome segregation PMID: 28441529
  3. MPS1 is a new marker of Purkinje Cells. PMID: 26708598
  4. We identified frequent recurrent (i.e. hotspot) mutation in the 5' untranslated region of RPS27 in ~10% of melanoma samples PMID: 24913145
  5. The data on genome context analysis indicates that the presence of MPS-1 in the blood is an indicator of oncogenesis PMID: 22798506
  6. This work is consistent with a critical role of RPMPS-1/S27 in the life cycle of various viruses and shows that disruption of viral ZFPs is potentially important to control and prevent deathly viral diseases PMID: 21518817
  7. study reveals a multilevel interplay between RPS27L/S27 and p53-MDM2 axis, with RPS27L functioning as a p53 target, a MDM2 substrate and a p53 regulator PMID: 21170087
  8. When MPS-1 is overexpressed, it has an extraribosomal function as a strong inhibitor of HNSCC tumor cell growth, which may be exerted by reduced paxillin gene expression. PMID: 19642098
  9. MPS-1 was overexpressed in 86% of the gastric cancer tissues and all gastric cancer cells. MPS-1 expression was significantly increased and corresponded with the tumor-node-metastasis clinical stage, and was significantly higher in the late stage. PMID: 16914586

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Involvement in disease
Diamond-Blackfan anemia 17 (DBA17)
Protein Families
Eukaryotic ribosomal protein eS27 family
Tissue Specificity
Expressed in a wide variety of actively proliferating cells and tumor tissues.
Database Links

HGNC: 10416

OMIM: 603702

KEGG: hsa:6232

STRING: 9606.ENSP00000357555

UniGene: Hs.546291

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