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RPS27 Antibody

Datasheet
Code CSB-PA020419ESR1HU
Size US$166
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  • Western Blotting(WB) - RPS27 Antibody

    Western blot
    All lanes: RPS27antibody at 2.76μg/ml
    Lane 1: Mouse liver tissue
    Lane 2: MCF-7 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 9 kDa
    Observed band size: 9 kDa

  • Immunohistochemistry(IHC) 1- RPS27 Antibody

    Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA020419ESR1HU at dilution of 1:100

  • Immunohistochemistry(IHC) 2- RPS27 Antibody

    Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA020419ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RPS27 Polyclonal antibody
Uniprot No.
P42677
Target Names
RPS27
Alternative Names
2610206D02Rik antibody; 3200001M24Rik antibody; 40S ribosomal protein S27 antibody; C530005D02Rik antibody; Metallopan stimulin 1 antibody; Metallopan-stimulin 1 antibody; Metallopanstimulin 1 antibody; Metallopanstimulin1 antibody; MPS 1 antibody; MPS-1 antibody; MPS1 antibody; pmn antibody; Ribosomal protein S27 antibody; Ribosomal protein S27 metallopanstimulin 1 antibody; rps27 antibody; RS27_HUMAN antibody; S27 antibody; snoRNA MBI 112 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human 40S ribosomal protein S27 protein (1-84AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

RPS27 Antibodies

RPS27 Proteins

Customer Reviews and Q&A

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Target Background

Function
Component of the small ribosomal subunit. Required for proper rRNA processing and maturation of 18S rRNAs.
Gene References into Functions
  1. Chloride anion behaves as a signaling effector for CFTR in the modulation of RPS27 expression. PMID: 28941802
  2. reveal how Mps1 dynamically modifies kinetochores to correct improper attachments and ensure faithful chromosome segregation PMID: 28441529
  3. MPS1 is a new marker of Purkinje Cells. PMID: 26708598
  4. We identified frequent recurrent (i.e. hotspot) mutation in the 5' untranslated region of RPS27 in ~10% of melanoma samples PMID: 24913145
  5. The data on genome context analysis indicates that the presence of MPS-1 in the blood is an indicator of oncogenesis PMID: 22798506
  6. This work is consistent with a critical role of RPMPS-1/S27 in the life cycle of various viruses and shows that disruption of viral ZFPs is potentially important to control and prevent deathly viral diseases PMID: 21518817
  7. study reveals a multilevel interplay between RPS27L/S27 and p53-MDM2 axis, with RPS27L functioning as a p53 target, a MDM2 substrate and a p53 regulator PMID: 21170087
  8. When MPS-1 is overexpressed, it has an extraribosomal function as a strong inhibitor of HNSCC tumor cell growth, which may be exerted by reduced paxillin gene expression. PMID: 19642098
  9. MPS-1 was overexpressed in 86% of the gastric cancer tissues and all gastric cancer cells. MPS-1 expression was significantly increased and corresponded with the tumor-node-metastasis clinical stage, and was significantly higher in the late stage. PMID: 16914586

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Involvement in disease
Diamond-Blackfan anemia 17 (DBA17)
Protein Families
Eukaryotic ribosomal protein eS27 family
Tissue Specificity
Expressed in a wide variety of actively proliferating cells and tumor tissues.
Database Links

HGNC: 10416

OMIM: 603702

KEGG: hsa:6232

STRING: 9606.ENSP00000357555

UniGene: Hs.546291

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