RPS27 Antibody

Code CSB-PA020419GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
RPS27
Alternative Names
2610206D02Rik antibody; 3200001M24Rik antibody; 40S ribosomal protein S27 antibody; C530005D02Rik antibody; Metallopan stimulin 1 antibody; Metallopan-stimulin 1 antibody; Metallopanstimulin 1 antibody; Metallopanstimulin1 antibody; MPS 1 antibody; MPS-1 antibody; MPS1 antibody; pmn antibody; Ribosomal protein S27 antibody; Ribosomal protein S27 metallopanstimulin 1 antibody; rps27 antibody; RS27_HUMAN antibody; S27 antibody; snoRNA MBI 112 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human RPS27
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the small ribosomal subunit. Required for proper rRNA processing and maturation of 18S rRNAs.
Gene References into Functions
  1. Chloride anion behaves as a signaling effector for CFTR in the modulation of RPS27 expression. PMID: 28941802
  2. reveal how Mps1 dynamically modifies kinetochores to correct improper attachments and ensure faithful chromosome segregation PMID: 28441529
  3. MPS1 is a new marker of Purkinje Cells. PMID: 26708598
  4. We identified frequent recurrent (i.e. hotspot) mutation in the 5' untranslated region of RPS27 in ~10% of melanoma samples PMID: 24913145
  5. The data on genome context analysis indicates that the presence of MPS-1 in the blood is an indicator of oncogenesis PMID: 22798506
  6. This work is consistent with a critical role of RPMPS-1/S27 in the life cycle of various viruses and shows that disruption of viral ZFPs is potentially important to control and prevent deathly viral diseases PMID: 21518817
  7. study reveals a multilevel interplay between RPS27L/S27 and p53-MDM2 axis, with RPS27L functioning as a p53 target, a MDM2 substrate and a p53 regulator PMID: 21170087
  8. When MPS-1 is overexpressed, it has an extraribosomal function as a strong inhibitor of HNSCC tumor cell growth, which may be exerted by reduced paxillin gene expression. PMID: 19642098
  9. MPS-1 was overexpressed in 86% of the gastric cancer tissues and all gastric cancer cells. MPS-1 expression was significantly increased and corresponded with the tumor-node-metastasis clinical stage, and was significantly higher in the late stage. PMID: 16914586

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Involvement in disease
Diamond-Blackfan anemia 17 (DBA17)
Protein Families
Eukaryotic ribosomal protein eS27 family
Tissue Specificity
Expressed in a wide variety of actively proliferating cells and tumor tissues.
Database Links

HGNC: 10416

OMIM: 603702

KEGG: hsa:6232

STRING: 9606.ENSP00000357555

UniGene: Hs.546291

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