RUFY1 Antibody

Code CSB-PA073117
Size US$297
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  • Western blot analysis of extracts from HeLa cells, using RUFY1 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RUFY1 Polyclonal antibody
Uniprot No.
Target Names
RUFY1
Alternative Names
3000002E04Rik antibody; FLJ22251 antibody; FYVE finger protein EIP1 antibody; FYVE-finger protein EIP1 antibody; La binding protein 1 antibody; La-binding protein 1 antibody; OTTHUMP00000161521 antibody; Rab4 interacting protein antibody; Rab4-interacting protein antibody; RABIP4 antibody; RUFY1 antibody; RUFY1_HUMAN antibody; RUN and FYVE domain containing 1 antibody; RUN and FYVE domain-containing protein 1 antibody; RUN and FYVE domains containing protein 1 antibody; ZFYVE12 antibody; Zinc finger FYVE domain containing protein 12 antibody; Zinc finger FYVE domain-containing protein 12 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human RUFY1.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.
Gene References into Functions
  1. RUFY1 may be involved in endolysosomal transport-a process known to be important to development of early onset AD. PMID: 28738127
  2. Data indicate that RUN and FYVE domain protein Rabip4'(RUFY1) interacts specifically and directly with adaptor protein complex AP-3. PMID: 23144738
  3. These findings suggest that Rab14 and Rab4 act sequentially, together with RUFY1. PMID: 20534812
  4. interaction with tyrosine kinase Etk PMID: 11877430
Subcellular Location
Cytoplasm. Early endosome membrane; Peripheral membrane protein.
Tissue Specificity
Broadly expressed, with highest levels in lung, testis, kidney and brain.
Database Links

HGNC: 19760

OMIM: 610327

KEGG: hsa:80230

STRING: 9606.ENSP00000325594

UniGene: Hs.306769

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