RUFY1 Antibody

Code CSB-PA839417ESR1HU
Size US$166
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Image
  • Western blot
    All lanes: RUFY1 antibody at 7.54μg/ml
    Lane 1: Mouse kidney tissue
    Lane 2: Mouse heart tissue
    Lane 3: Mouse lung tissue
    Lane 4: Mouse gonadal tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 80, 70, 45 kDa
    Observed band size: 80 kDa

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA839417ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RUFY1 Polyclonal antibody
Uniprot No.
Target Names
RUFY1
Alternative Names
3000002E04Rik antibody; FLJ22251 antibody; FYVE finger protein EIP1 antibody; FYVE-finger protein EIP1 antibody; La binding protein 1 antibody; La-binding protein 1 antibody; OTTHUMP00000161521 antibody; Rab4 interacting protein antibody; Rab4-interacting protein antibody; RABIP4 antibody; RUFY1 antibody; RUFY1_HUMAN antibody; RUN and FYVE domain containing 1 antibody; RUN and FYVE domain-containing protein 1 antibody; RUN and FYVE domains containing protein 1 antibody; ZFYVE12 antibody; Zinc finger FYVE domain containing protein 12 antibody; Zinc finger FYVE domain-containing protein 12 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human RUN and FYVE domain-containing protein 1 protein (439-708AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.
Gene References into Functions
  1. RUFY1 may be involved in endolysosomal transport-a process known to be important to development of early onset AD. PMID: 28738127
  2. Data indicate that RUN and FYVE domain protein Rabip4'(RUFY1) interacts specifically and directly with adaptor protein complex AP-3. PMID: 23144738
  3. These findings suggest that Rab14 and Rab4 act sequentially, together with RUFY1. PMID: 20534812
  4. interaction with tyrosine kinase Etk PMID: 11877430
Subcellular Location
Cytoplasm. Early endosome membrane; Peripheral membrane protein.
Tissue Specificity
Broadly expressed, with highest levels in lung, testis, kidney and brain.
Database Links

HGNC: 19760

OMIM: 610327

KEGG: hsa:80230

STRING: 9606.ENSP00000325594

UniGene: Hs.306769

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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