Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Recombinant Human Sodium channel protein type 11 subunit alpha protein (403-551AA)
Raised in :
Species Reactivity :
Tested Applications :
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization.