SEC16B Antibody

Datasheet

Code	CSB-PA853439LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA853439LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SEC16B Polyclonal antibody

Uniprot No.

Q96JE7

Target Names

SEC16B

Alternative Names

DKFZp686C2486 antibody; FLJ23871 antibody; FLJ25761 antibody; FLJ33652 antibody; FLJ36620 antibody; KIAA1928 antibody; Leucine zipper transcription regulator 2 antibody; LZTR 2 antibody; PGPR p117 antibody; Protein SEC16 homolog B antibody; Protein transport protein Sec16B antibody; Regucalcin gene promoter region related protein antibody; Regucalcin gene promoter region related protein p117 antibody; Regucalcin gene promoter region-related protein p117 antibody; RGPR antibody; RGPR p117 antibody; RGPR-p117 antibody; SC16B_HUMAN antibody; SEC16 homolog B (S. cerevisiae) antibody; SEC16 homolog B antibody; SEC16B antibody; SEC16S antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Protein transport protein Sec16B protein (5-304AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SEC16B Antibody (Product code: CSB-PA853439LA01HU) is Non-conjugated. For SEC16B Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA853439LB01HU	SEC16B Antibody, HRP conjugated	ELISA
FITC	CSB-PA853439LC01HU	SEC16B Antibody, FITC conjugated
Biotin	CSB-PA853439LD01HU	SEC16B Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes.

Gene References into Functions

Significant associations were identified at 3.5 years for SEC16B rs10913469 with dietary parameters PMID: 27005443
describe characterization of the localization and dynamics of Sec16B relative to Sec16A, provide evidence that Sec16B is likely a minor or perhaps specialized form of Sec16, and that it is not functionally redundant with S PMID: 22355596
Data show that knockdown of Sec16B but not Sec16A by RNAi affected the morphology of peroxisomes, inhibited the transport of Pex16 from the ER to peroxisomes, and suppressed expression of Pex3. PMID: 21768384
Data show that SNPs in SEC16B and TMEM18 were significantly associated with obesity, and the SNPs in GNPDA2, BDNF, FAIM2 and MC4R were marginally associated with obesity in Japanese. PMID: 19851340
Mammalian cells contain two distinct Sec16 homologues: a large protein Sec16L of 2154 aa and a smaller protein Sec16S of 1060 aa. PMID: 17192411

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Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.

Protein Families

SEC16 family

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 30301

OMIM: 612855

KEGG: hsa:89866

STRING: 9606.ENSP00000308339

UniGene: Hs.149540

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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