SEC16B Antibody, Biotin conjugated

Datasheet

Code	CSB-PA853439LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SEC16B Polyclonal antibody

Uniprot No.

Q96JE7

Target Names

SEC16B

Alternative Names

DKFZp686C2486 antibody; FLJ23871 antibody; FLJ25761 antibody; FLJ33652 antibody; FLJ36620 antibody; KIAA1928 antibody; Leucine zipper transcription regulator 2 antibody; LZTR 2 antibody; PGPR p117 antibody; Protein SEC16 homolog B antibody; Protein transport protein Sec16B antibody; Regucalcin gene promoter region related protein antibody; Regucalcin gene promoter region related protein p117 antibody; Regucalcin gene promoter region-related protein p117 antibody; RGPR antibody; RGPR p117 antibody; RGPR-p117 antibody; SC16B_HUMAN antibody; SEC16 homolog B (S. cerevisiae) antibody; SEC16 homolog B antibody; SEC16B antibody; SEC16S antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Protein transport protein Sec16B protein (5-304AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes.

Gene References into Functions

Significant associations were identified at 3.5 years for SEC16B rs10913469 with dietary parameters PMID: 27005443
describe characterization of the localization and dynamics of Sec16B relative to Sec16A, provide evidence that Sec16B is likely a minor or perhaps specialized form of Sec16, and that it is not functionally redundant with S PMID: 22355596
Data show that knockdown of Sec16B but not Sec16A by RNAi affected the morphology of peroxisomes, inhibited the transport of Pex16 from the ER to peroxisomes, and suppressed expression of Pex3. PMID: 21768384
Data show that SNPs in SEC16B and TMEM18 were significantly associated with obesity, and the SNPs in GNPDA2, BDNF, FAIM2 and MC4R were marginally associated with obesity in Japanese. PMID: 19851340
Mammalian cells contain two distinct Sec16 homologues: a large protein Sec16L of 2154 aa and a smaller protein Sec16S of 1060 aa. PMID: 17192411

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Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.

Protein Families

SEC16 family

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 30301

OMIM: 612855

KEGG: hsa:89866

STRING: 9606.ENSP00000308339

UniGene: Hs.149540

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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