SEMA3G Antibody

Code CSB-PA448223
Size US$166
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Image
  • Gel: 8%SDS-PAGE, Lysate: 50 μg, Lane: Jurkat cells, Primary antibody: CSB-PA448223(SEMA3G Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 minutes
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Product Details

Uniprot No.
Target Names
SEMA3G
Alternative Names
FLJ00014 antibody; MGC119473 antibody; Sem2 antibody; SEM3G_HUMAN antibody; Sema domain immunoglobulin domain (Ig) short basic domain secreted (semaphorin) 3G antibody; Sema3g antibody; Semaphorin 3G antibody; Semaphorin sem2 antibody; Semaphorin-3G antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human SEMA3G
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
WB 1:200-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Has chemorepulsive activities for sympathetic axons. Ligand of NRP2.
Gene References into Functions
  1. Results indicate that Sema3G protein is secreted by podocytes and protects them from inflammatory kidney diseases and diabetic nephropathy. PMID: 27180624
  2. Results identify Sema3g as one of the downstream effectors of PPAR-gamma, which is centrally involved in regulating endothelial cell migration. PMID: 25335934
  3. overexpressed SEMA3G inhibited the migratory and invasive behavior of U251MG cancer cells PMID: 22562223
  4. Identify Sema3G as a primarily endothelial cell-expressed class 3 semaphorin that controls endothelial and smooth muscle cell functions in autocrine and paracrine manners. PMID: 20947821
  5. In gliomas, SEMA3B, SEMA3G and NRP2 expressions were related to prolonged survival PMID: 18781179
  6. Sema3G inhibits tumor progression from MDA-MB-435 but not from MDA-MB-231 cancer cells. It inhibits tumor angiogenesis in MDA-MB-231 cells. PMID: 18818766

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Subcellular Location
Secreted.
Protein Families
Semaphorin family
Database Links

HGNC: 30400

KEGG: hsa:56920

STRING: 9606.ENSP00000231721

UniGene: Hs.59729

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