All
  • All
  • ELISA Kit
  • Protein
  • Antibody
  • Molecular Biology Product
  • Small Molecule
  • Peptide
All
  • All
  • ELISA Kit
  • Protein
  • Antibody
  • Molecular Biology Product
  • Small Molecule
  • Peptide

SEMA4C Antibody

Datasheet
Citations (1)
Code CSB-PA787154
Size US$166
Order now
Image
  • Immunohistochemistry (IHC) - SEMA4C Antibody
    The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA787154(SEMA4C Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • Immunohistochemistry (IHC) P- SEMA4C Antibody
    The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA787154(SEMA4C Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Uniprot No.
Q9C0C4
Target Names
SEMA4C
Alternative Names
KIAA1739 antibody; M-SEMA-F antibody; S4c antibody; SEM4C_HUMAN antibody; Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C antibody; SEMA4C antibody; SEMACL1 antibody; SEMAF antibody; SEMAI antibody; Semaphorin-4C antibody; UNQ5855/PRO34487 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human SEMA4C
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:25-1:100
Protocols
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

Related Products

SEMA4C Antibodies

SEMA4C Proteins

Customer Reviews and Q&A

■ Customer Reviews
Average Rating:
5.0 - 1 reviews

Submit a Review here

Applications : Immunohistochemistry

Review: Immunohistochemistry on paw punches, DRG and spinal cord.

By Anonymous

Read more reviews >>

Target Background

Function
Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Gene References into Functions
  1. Tumor-associated LECs produce sSEMA4C to promote lymphatic metastasis of tumors. PMID: 27401250
  2. ectopic expression of miR-25-3p reversed the epithelial-mesenchymal transition phenotype and sensitized cisplatin-resistant cervical cancer cells to cisplatin via targeting Sema4C PMID: 27743413
  3. Data show that G-protein-coupled receptor kinase-interacting protein 1 (GIT1) and semaphorin 4C (SEMA4C) were found to have putative microRNA miR-138 binding sites in their 3' untranslated region (3'UTRs). PMID: 26283050
  4. Suggest that up-regulation of miR-125b or targeting Sema4C could serve as novel approaches to reverse chemotherapy resistance in breast cancers. PMID: 25605244
  5. Data suggest that Erbin can interact with Sema4C, and co-expression of Erbin blocks the process of Sema4C-induced epithelial-mesenchymal transition. PMID: 24142719
  6. There is a high expression of Sema4C in esophageal cancer, gastric cancer and rectal cancer, and expression is strongly correlated with lymphatic metastasis. PMID: 22944267
  7. High Sema4C is associated with epithelial-mesenchymal transition and renal fibrosis. PMID: 20959347

Show More

Hide All

Subcellular Location
Cell junction, synapse, postsynaptic density membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein.
Protein Families
Semaphorin family
Database Links

HGNC: 10731

OMIM: 604462

KEGG: hsa:54910

STRING: 9606.ENSP00000306844

UniGene: Hs.516220

Promotions
Reward For Reviews
Free antibody trial
Contact Us

  Email: [email protected]
  Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Related Articles
SEMA4D/CD100: As an Important Immunoregulator to Improve Immunotherapy Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?
CUSABIO guaranteed quality
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of email
Email
[email protected]
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2025 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Privacy Policy
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*