SLC16A11 Antibody

Datasheet
Code CSB-PA843323LA01HU
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Size US$299
Uniprot No. Q8NCK7
Image
  • Western Blot
    Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate
    All lanes: SLC16A11 antibody at 3.8µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 48 kDa
    Observed band size: 48 kDa

  • Immunofluorescence staining of A549 cells with CSB-PA843323LA01HU at 1:150, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Immunogen Recombinant Human Monocarboxylate transporter 11 protein (428-471AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200
Relevance Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane (Probable). Probably involved in hepatic lipid metabolism: overexpression results in an increase of triacylglycerol(TAG) levels, small increases in intracellular diacylglycerols and decreases in lysophosphatidylcholine, cholesterol ester and sphingomyelin lipids.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Monocarboxylate transporter 11 (MCT 11) (Solute carrier family 16 member 11), SLC16A11, MCT11
Immunogen Species Human
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
Research Area Signal Transduction
Target Names SLC16A11
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Proton-linked monocarboxylate transporter. It catalyzes the transport of pyruvate across the plasma membrane
Involvement in disease Diabetes mellitus, non-insulin-dependent (NIDDM)
Subcellular Location Endoplasmic reticulum membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein
Protein Families Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13) family
Tissue Specificity Expressed in liver, salivary gland and thyroid.
Database Links

HGNC: 23093

OMIM: 125853

KEGG: hsa:162515

STRING: 9606.ENSP00000310490

UniGene: Hs.336564

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