SLC1A2 Antibody, FITC conjugated

Datasheet
Code CSB-PA021433LC01HU
Size US$299
Uniprot No. P43004
Protocols ELISA Protocol
Immunogen Recombinant Human Excitatory amino acid transporter 2 protein (460-574AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2), SLC1A2, EAAT2 GLT1
Immunogen Species Homo sapiens (Human)
Research Area Neuroscience
Target Names SLC1A2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate
Involvement in disease Epileptic encephalopathy, early infantile, 41 (EIEE41)
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families Dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family, SLC1A2 subfamily
Database Links

HGNC: 10940

OMIM: 600300

KEGG: hsa:6506

STRING: 9606.ENSP00000278379

UniGene: Hs.502338

Pathway Glutamatergic synapse

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