Code | CSB-RA051685A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:2000 |
FC | 1:50-1:200 |
The SLC1A2 recombinant monoclonal antibody is synthesized in vitro through a systematic process. Initially, SLC1A2 antibody genes are isolated from B cells derived from immunoreactive rabbits. These genes undergo amplification and are cloned into phage vectors, which are subsequently introduced into mammalian cell lines to facilitate the generation of functional antibodies in significant quantities. The resulting SLC1A2 recombinant monoclonal antibody is purified from the culture supernatant of the transfected cell lines through affinity chromatography. It can recognize human SLC1A2 protein in three applications, including ELISA, WB, and FC.
SLC1A2, or EAAT2/GLT-1, is a crucial protein responsible for clearing excess glutamate from the synaptic cleft, preventing excitotoxicity, and maintaining proper neurotransmission and brain function. Its role in glutamate transport is fundamental to neuronal health, synaptic plasticity, and the prevention of neurological disorders associated with glutamate dysregulation.
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