SLC25A10 Antibody

Code CSB-PA883371LA01HU
Size US$166
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  • Western blot
    All lanes: SLC25A10 antibody at 16µg/ml
    Lane 1: Mouse liver tissue
    Lane 2: Mouse kidney tissue
    Lane 3: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 32, 33 kDa
    Observed band size: 32, 24 kDa

  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA883371LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human prostata cancer using CSB-PA883371LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLC25A10 Polyclonal antibody
Uniprot No.
Target Names
SLC25A10
Alternative Names
SLC25A10; DIC; Mitochondrial dicarboxylate carrier; Solute carrier family 25 member 10
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Mitochondrial dicarboxylate carrier protein (124-162AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SLC25A10 Antibody (Product code: CSB-PA883371LA01HU) is Non-conjugated. For SLC25A10 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA883371LB01HU SLC25A10 Antibody, HRP conjugated ELISA
FITC CSB-PA883371LC01HU SLC25A10 Antibody, FITC conjugated
Biotin CSB-PA883371LD01HU SLC25A10 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane.
Gene References into Functions
  1. study identifies novel genes associated with insulin sensitivity in adipocytes in women independently of obesity. KFL15 and SLC25A10 are inhibitors of insulin-stimulated lipogenesis under conditions when glucose transport is the rate limiting step PMID: 28570579
  2. the SLC25A10 carrier plays an important role in regulating redox homeostasis to protect confluent cells against oxidative stress. PMID: 25797253
  3. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
  4. SLC25A10 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
  5. Slc25a10 plays an important role in supplying malate for citrate transport required for fatty acid synthesis and its inhibition might effectively reduce lipid accumulation in adipose tissues PMID: 16027120

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Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein Families
Mitochondrial carrier (TC 2.A.29) family
Tissue Specificity
Present in high amounts in liver and kidney, and at lower levels in all the other tissues analyzed.
Database Links

HGNC: 10980

OMIM: 606794

KEGG: hsa:1468

STRING: 9606.ENSP00000345580

UniGene: Hs.548187

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