SLC25A14 Antibody, HRP conjugated

Datasheet

Code	CSB-PA021480LB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SLC25A14 Polyclonal antibody

Uniprot No.

O95258

Target Names

SLC25A14

Alternative Names

SLC25A14; BMCP1; UCP5; UNQ791/PRO1682; Brain mitochondrial carrier protein 1; BMCP-1; Mitochondrial uncoupling protein 5; UCP 5; Solute carrier family 25 member 14

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Brain mitochondrial carrier protein 1 protein (55-111AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Participates in the mitochondrial proton leak measured in brain mitochondria.

Gene References into Functions

Increased expression of cerebral UCP5 and UCP4 is observed in a model of high altitude hypoxia and mitochondrial oxidative phosphorylation deficiency. PMID: 23266757
Neuronal UCP5 exhibits transmembrane chloride transport activity. PMID: 22524567
observed significant associations between genetic variants in the SIRT6 and UCP5 genes and atherosclerotic plaque PMID: 22087257
The enhanced level of UCP5 is associated to mitochondrial dysfunction in colonic cells. PMID: 19910678
expressed in skeletal muscle as three different isoforms; expression level of UCP5SI positively correlated with resting metabolic rate and lipid oxidation rate during a euglycemic clamp with infusion of insulin at a physiologic concentration PMID: 12051969
UCP5 might be physiologically important in the pathology of oxidative stress-induced neurodegeneration PMID: 16941493
The brain may respond to neuroprotection through the increased expression of UCP5 under ischemic conditions. PMID: 18018477

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Subcellular Location

Mitochondrion inner membrane; Multi-pass membrane protein.

Protein Families

Mitochondrial carrier (TC 2.A.29) family

Tissue Specificity

Mainly expressed in brain. Some expression in testis and pituitary.

Database Links

HGNC: 10984

OMIM: 300242

KEGG: hsa:9016

STRING: 9606.ENSP00000218197

UniGene: Hs.194686

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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