SLC30A9 Antibody

Code CSB-PA216479
Size US$297
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  • Western blot analysis of extracts from HepG2 cells, using SLC30A9 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLC30A9 Polyclonal antibody
Uniprot No.
Target Names
SLC30A9
Alternative Names
SLC30A9; C4orf1; HUEL; Zinc transporter 9; ZnT-9; Human embryonic lung protein; HuEL; Solute carrier family 30 member 9
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human SLC30A9.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a zinc transporter involved in intracellular zinc homeostasis. Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt-responsive genes.
Gene References into Functions
  1. Expression of zinc transporters ZIP4, ZIP14 and ZnT9 in hepatic carcinogenesis-An immunohistochemical study PMID: 29895370
  2. SLC30A9 has zinc transport properties affecting intracellular zinc homeostasis, and that the molecular mechanism of the disease is through defective function of this novel activity of SLC30A9 PMID: 28334855
  3. ZNT9 expression in glioma tumors was not associated with tumor grade or IDH1 mutation status. PMID: 25921144
  4. Results indicate that HUEL, which shares significant homology with the DNA-binding domain of XPA, is likely to be a conserved, housekeeping gene that is intimately linked with cellular replication, DNA synthesis and/or transcriptional regulation. PMID: 11906820
  5. hZnT-9 was expressed at low levels in leukocytes. PMID: 17971500

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Involvement in disease
Birk-Landau-Perez syndrome (BILAPES)
Subcellular Location
Membrane; Multi-pass membrane protein. Nucleus. Cytoplasm. Cytoplasmic vesicle. Endoplasmic reticulum.
Protein Families
Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
Tissue Specificity
Ubiquitously expressed in fetal and adult tissues and cancer cell lines.
Database Links

HGNC: 1329

OMIM: 604604

KEGG: hsa:10463

STRING: 9606.ENSP00000264451

UniGene: Hs.479634

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