SLC32A1 Antibody

Code CSB-PA863984LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Mouse brain tissue
    All lanes: SLC32A1 antibody at 3.4μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 58 kDa
    Observed band size: 58 kDa

  • Immunohistochemistry of paraffin-embedded human eye tissue using CSB-PA863984LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA863984LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLC32A1 Polyclonal antibody
Uniprot No.
Target Names
SLC32A1
Alternative Names
bA122O1.1 antibody; GABA and glycine transporter antibody; hVIAAT antibody; SLC32A 1 antibody; Slc32a1 antibody; solute carrier family 32 (GABA vesicular transporter) member 1 antibody; Solute carrier family 32 member 1 antibody; Vesicular GABA Amino Acid Transporter antibody; Vesicular GABA transporter antibody; Vesicular inhibitory amino acid transporter antibody; VGAT antibody; VIAAT antibody; VIAAT_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Vesicular inhibitory amino acid transporter protein (14-118AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SLC32A1 Antibody (Product code: CSB-PA863984LA01HU) is Non-conjugated. For SLC32A1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA863984LB01HU SLC32A1 Antibody, HRP conjugated ELISA
FITC CSB-PA863984LC01HU SLC32A1 Antibody, FITC conjugated
Biotin CSB-PA863984LD01HU SLC32A1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

The SLC32A1 antibody can be used to recognize the human and mouse SLC32A1 protein. When a rabbit received an injection of the recombinant human SLC32A1 protein (14-118aa), an immune response occurred in the rabbit producing large amounts of antibodies against the SLC32A1 protein. The rabbit's blood was collected and isolated to get the anti-serum, which was subjected to protein G purification to obtain the SLC32A1 polyclonal antibody (purity 95%+). This SLC32A1 antibody has accessed its specificity in ELISA, WB, IHC, and IF applications.

SLC32A1, also known as VIAAT, is a membrane protein responsible for transporting inhibitory neurotransmitters, such as gamma-aminobutyric acid (GABA) and glycine, into synaptic vesicles in neurons. It plays an important role in the regulation of neuronal excitability and inhibition in the nervous system. Dysfunction of SLC32A1 has been associated with several neurological and psychiatric disorders, including epilepsy, schizophrenia, and autism.

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Target Background

Function
Involved in the uptake of GABA and glycine into the synaptic vesicles.
Gene References into Functions
  1. VIATT has been identified in horizontal cells of the adult outer retina in culture, either at their terminals or throughout the entire cell. PMID: 12115694
  2. Subjects with schizophrenia exhibited expression deficits in GABA transpter 1. PMID: 17471287
Subcellular Location
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein Families
Amino acid/polyamine transporter 2 family
Tissue Specificity
Retina. Expressed throughout the horizontal cells or more specifically at the terminals.
Database Links

HGNC: 11018

OMIM: 616440

KEGG: hsa:140679

STRING: 9606.ENSP00000217420

UniGene: Hs.179080

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