SLC32A1 Antibody

Datasheet

Code	CSB-PA863984LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Y79 whole cell lysate(30µg), SY5Y whole cell lysate(30µg), Mouse Brain tissue lysate(30µg),Rat Brain tissue lysate(30µg) All lanes: SLC32A1 antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/40000 dilution Predicted band size: 58 kDa Observed band size: 58 kDa Exposure time: 120s
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SLC32A1 Polyclonal antibody

Uniprot No.

Q9H598

Target Names

SLC32A1

Alternative Names

bA122O1.1 antibody; GABA and glycine transporter antibody; hVIAAT antibody; SLC32A 1 antibody; Slc32a1 antibody; solute carrier family 32 (GABA vesicular transporter) member 1 antibody; Solute carrier family 32 member 1 antibody; Vesicular GABA Amino Acid Transporter antibody; Vesicular GABA transporter antibody; Vesicular inhibitory amino acid transporter antibody; VGAT antibody; VIAAT antibody; VIAAT_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from SLC32A1

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

The SLC32A1 antibody can be used to recognize the human and mouse SLC32A1 protein. When a rabbit received an injection of the recombinant human SLC32A1 protein (14-118aa), an immune response occurred in the rabbit producing large amounts of antibodies against the SLC32A1 protein. The rabbit's blood was collected and isolated to get the anti-serum, which was subjected to protein G purification to obtain the SLC32A1 polyclonal antibody (purity 95%⁺). This SLC32A1 antibody has accessed its specificity in ELISA, WB, IHC, and IF applications.

SLC32A1, also known as VIAAT, is a membrane protein responsible for transporting inhibitory neurotransmitters, such as gamma-aminobutyric acid (GABA) and glycine, into synaptic vesicles in neurons. It plays an important role in the regulation of neuronal excitability and inhibition in the nervous system. Dysfunction of SLC32A1 has been associated with several neurological and psychiatric disorders, including epilepsy, schizophrenia, and autism.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Involved in the uptake of GABA and glycine into the synaptic vesicles.

Gene References into Functions

VIATT has been identified in horizontal cells of the adult outer retina in culture, either at their terminals or throughout the entire cell. PMID: 12115694
Subjects with schizophrenia exhibited expression deficits in GABA transpter 1. PMID: 17471287

Subcellular Location

Cytoplasmic vesicle membrane; Multi-pass membrane protein.

Protein Families

Amino acid/polyamine transporter 2 family

Tissue Specificity

Retina. Expressed throughout the horizontal cells or more specifically at the terminals.

Database Links

HGNC: 11018

OMIM: 616440

KEGG: hsa:140679

STRING: 9606.ENSP00000217420

UniGene: Hs.179080

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Protein Service

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Related pathways

Secreted Extracellular Vesicles

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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