SLC4A8 Antibody

Code CSB-PA021673GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SLC4A8
Alternative Names
Electroneutral Na(+)-driven Cl-HCO3 exchanger antibody; Electroneutral sodium bicarbonate exchanger 1 antibody; k-NBC3 antibody; S4A8_HUMAN antibody; Slc4a8 antibody; SLC4A8 protein antibody; Solute carrier family 4 member 8 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SLC4A8
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
Gene References into Functions
  1. This study confirmed the presence in human cDNA of mouse NDCBE-like transcripts (human NDCBE-A) and three novel transcripts NDCBE-C, NDCBE-D, and NDCBE-D'. PMID: 18577713
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Anion exchanger (TC 2.A.31) family
Tissue Specificity
Expressed in the pyramidal cells of the hippocampus (at protein level). Highly expressed in all major regions of the brain, spinal column and in testis, and moderate levels in trachea, thyroid and medulla region of kidney. Low expression levels observed i
Database Links

HGNC: 11034

OMIM: 605024

KEGG: hsa:9498

STRING: 9606.ENSP00000405812

UniGene: Hs.4749

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