SMOC2 Antibody

Datasheet

Code	CSB-PA169309
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA169309(SMOC2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA169309(SMOC2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: CSB-PA169309(SMOC2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9H3U7

Target Names

SMOC2

Alternative Names

bA270C4A.1 antibody; bA37D8.1 (secreted modular calcium binding protein 2) antibody; bA37D8.1 antibody; dJ421D16.1 (novel thyroglobulin type 1 repeat containing protein) antibody; dJ421D16.1 antibody; MST117 antibody; MSTP117 antibody; MSTP140 antibody; Secreted modular calcium binding protein 2 antibody; Secreted modular calcium-binding protein 2 antibody; SMAP 2 antibody; SMAP-2 antibody; SMAP2 antibody; SMOC 2 antibody; SMOC-2 antibody; SMOC2 antibody; SMOC2_HUMAN antibody; Smooth muscle associated protein 2 antibody; Smooth muscle-associated protein 2 antibody; SPARC related modular calcium binding 2 antibody; SPARC-related modular calcium-binding protein 2 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide of Human SMOC2

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000
IHC	1:25-1:100

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Promotes matrix assembly and cell adhesiveness. Can stimulate endothelial cell proliferation, migration, as well as angiogenesis.

Gene References into Functions

SMOC2 was highly expressed in both peritoneal and endometrioma lesions. Considering that the genes studied participate either directly or indirectly in cellular processes that can lead to cell migration, angiogenesis, and inappropriate invasion, it is possible that the deregulation of these genes caused the development and maintenance of ectopic tissue. PMID: 28678915
The expression of Smoc2 was significantly higher in hepatocellular carcinoma (HCC) tissues compared with corresponding non-tumor liver tissues. Smoc2 promotes the proliferation of HCC cells through accelerating cell cycle progression. PMID: 28018113
L1-mediated CRC progression involves the acquisition of a stem cell-like phenotype, and that SMOC-2 elevation is necessary for L1-mediated induction of more aggressive/invasive CRC properties. PMID: 25915847
could not detect an association between SMOC2 gene and AMD. This study tests the candidacy of SMOC2 gene to the etiology of AMD PMID: 22964816
SMOC2 SNP may play a role in autoimmune thyroid disease susceptibility as a dominant polymorphism. PMID: 23463390
mutation in exon 8 of the SMOC2 gene linked to oligodontia PMID: 23317772
Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2, causing major dental developmental defects PMID: 22152679
The variant rs13208776 in SMOC2 gene does not play a major role in increasing the risk of vitiligo in Jordanian Arab patients. PMID: 20965805
SMOC2 is a risk locus for generalized vitiligo and perhaps other autoimmune diseases PMID: 19890347
identification of gene, chromosome mapping PMID: 12741954
SMOC-2 is a novel angiogenic factor that potentiates angiogenic effects of growth factors PMID: 16774925
We tested association between SMOC2 polymorphisms and FEV(1) and FVC. SMOC2 might play an important role in the determination of FEV(1) and FVC PMID: 17204727
Although this study specifies rat, the authors studied and discussed the human gene in this study as well. PMID: 12031507

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Involvement in disease

Dentin dysplasia 1 (DTDP1)

Subcellular Location

Secreted, extracellular space, extracellular matrix, basement membrane.

Database Links

HGNC: 20323

OMIM: 125400

KEGG: hsa:64094

STRING: 9606.ENSP00000346537

UniGene: Hs.487200

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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