SPATA16 Antibody, Biotin conjugated

Code CSB-PA871597LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SPATA16 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
NYD SP12 antibody; NYD-SP12 antibody; NYDSP12 antibody; SPATA16 antibody; Spermatogenesis associated 16 antibody; Spermatogenesis-associated protein 16 antibody; SPGF6 antibody; SPT16_HUMAN antibody; Testis development protein antibody; Testis development protein NYD-SP12 antibody; Testis specific Golgi protein antibody
Raised in
Species Reactivity
Recombinant Human Spermatogenesis-associated protein 16 protein (238-475AA)
Immunogen Species
Homo sapiens (Human)
Purification Method
>95%, Protein G purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion.
Gene References into Functions
  1. This study demonstrates that Spata16 is indispensable for male fertility in mice, as well as in humans. PMID: 29065458
  2. Mutation of SPATA16 is associated with globozoospermia. PMID: 27086357
  3. Case Report: report of a pregnancy obtained in a man with homozygous SPATA16 mutated globozoospermia. PMID: 24825417
  4. results suggest that NYD-SP12 is involved in spermatogenesis, and that NYD-SP12-encoded protein might function in the Golgi apparatus PMID: 12529416
  5. study demonstrated NYD-SP12 protein was involved in the formation of the acrosome during spermatogenesis PMID: 16372119
  6. Results indicate that NYD-SP12 evolves rapidly in both the human and the chimpanzee lineages, which is likely caused by Darwinian positive selection and/or sexual selection. PMID: 17665087
  7. consanguineous family with three affected brothers, in whom we have identified a homozygous mutation in the spermatogenesis-specific gene SPATA16. This is the first example of a nonsyndromic male infertility condition caused by an autosomal gene defect. PMID: 17847006

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Involvement in disease
Spermatogenic failure 6 (SPGF6)
Subcellular Location
Golgi apparatus. Note=Localized to the perinuclear region.
Protein Families
SPATA16 family
Tissue Specificity
Expressed in testis.
Database Links

HGNC: 29935

OMIM: 102530

KEGG: hsa:83893

STRING: 9606.ENSP00000341765

UniGene: Hs.444236

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