STARD5 Antibody

Code CSB-PA022804GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
STARD5
Alternative Names
STARD5 antibody; StAR-related lipid transfer protein 5 antibody; START domain-containing protein 5 antibody; StARD5 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human STARD5
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.
Gene References into Functions
  1. Studies show the 3 steroidogenic acute regulatory-related lipid transfer (START) domain proteins StarD4, StarD5 and StarD6 have a similar lipid binding pocket specific for sterols (cholesterol in particular), but differing regulation and localization. PMID: 24440759
  2. StarD4 is regulated by sterols via SREBP-2, and StarD5 is activated by ER stress cholesterol metabolism; they serve different functions PMID: 15760897
  3. demonstrated StarD5 protein in liver cytosolic fractions only, suggesting StarD5 as a directional cytosolic sterol carrier PMID: 15897605
  4. The presence of StarD5 different human liver cells that are related to inflammatory processes provides new clues to its role of in free sterol transport in the cells and in lipid-mediated atherogenesis. PMID: 16534142
  5. Data support STARD5 functioning in kidney, specifically within proximal tubule cells, and suggest a role in ER-associated cholesterol transport. PMID: 19474188

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Database Links

HGNC: 18065

OMIM: 607050

KEGG: hsa:80765

STRING: 9606.ENSP00000304032

UniGene: Hs.513075

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