STRA8 Antibody, FITC conjugated

Code CSB-PA767212LC01HU
Size US$299
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) STRA8 Polyclonal antibody
Uniprot No. Q7Z7C7
Target Names STRA8
Alternative Names
Stimulated by retinoic acid 8 antibody; stimulated by retinoic acid 8 homolog antibody; Stimulated by retinoic acid Gene 8 antibody; stimulated by retinoic acid gene 8 homolog antibody; Stimulated by retinoic acid gene 8 protein homolog antibody; STRA 8 antibody; STRA8 antibody; STRA8_HUMAN antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Stimulated by retinoic acid gene 8 protein homolog protein (115-241AA)
Immunogen Species Homo sapiens (Human)
Conjugate FITC
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis.
Gene References into Functions
  1. The genetic variant rs10269148 of STRA8 gene shows higher risk of spermatogenic impairment in the groups of abnormospermia than the controls PMID: 23320086
  2. Functional characterization of an homologous mouse gene. PMID: 18799751
  3. Observational study of gene-disease association. (HuGE Navigator) PMID: 20378615
  4. Expression restricted to testis (STRA8) PMID: 12489526
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Expressed specifically in testis and fetal ovaries.
Database Links

HGNC: 30653

OMIM: 609987

KEGG: hsa:346673

STRING: 9606.ENSP00000275764

UniGene: Hs.592279

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