STRA8 Antibody, HRP conjugated

Code CSB-PA767212LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) STRA8 Polyclonal antibody
Uniprot No.
Target Names
STRA8
Alternative Names
Stimulated by retinoic acid 8 antibody; stimulated by retinoic acid 8 homolog antibody; Stimulated by retinoic acid Gene 8 antibody; stimulated by retinoic acid gene 8 homolog antibody; Stimulated by retinoic acid gene 8 protein homolog antibody; STRA 8 antibody; STRA8 antibody; STRA8_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Stimulated by retinoic acid gene 8 protein homolog protein (115-241AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis.
Gene References into Functions
  1. The genetic variant rs10269148 of STRA8 gene shows higher risk of spermatogenic impairment in the groups of abnormospermia than the controls PMID: 23320086
  2. Functional characterization of an homologous mouse gene. PMID: 18799751
  3. Observational study of gene-disease association. (HuGE Navigator) PMID: 20378615
  4. Expression restricted to testis (STRA8) PMID: 12489526
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Expressed specifically in testis and fetal ovaries.
Database Links

HGNC: 30653

OMIM: 609987

KEGG: hsa:346673

STRING: 9606.ENSP00000275764

UniGene: Hs.592279

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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