STRA8 Antibody

Code CSB-PA767212LA01HU
Size US$299
Image
  • Western Blot
    Positive WB detected in: MCF-7 whole cell lysate, Jurkat whole cell lysate
    All lanes: STRA8 antibody at 3.4μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 37 kDa
    Observed band size: 60 kDa

  • IHC image of CSB-PA767212LA01HU diluted at 1:500 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) STRA8 Polyclonal antibody
Uniprot No. Q7Z7C7
Target Names STRA8
Alternative Names Stimulated by retinoic acid 8 antibody; stimulated by retinoic acid 8 homolog antibody; Stimulated by retinoic acid Gene 8 antibody; stimulated by retinoic acid gene 8 homolog antibody; Stimulated by retinoic acid gene 8 protein homolog antibody; STRA 8 antibody; STRA8 antibody; STRA8_HUMAN antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Stimulated by retinoic acid gene 8 protein homolog protein (115-241AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated

The STRA8 Antibody (Product code: CSB-PA767212LA01HU) is Non-conjugated. For STRA8 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA767212LB01HU STRA8 Antibody, HRP conjugated ELISA
FITC CSB-PA767212LC01HU STRA8 Antibody, FITC conjugated
Biotin CSB-PA767212LD01HU STRA8 Antibody, Biotin conjugated ELISA
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:500-1:1000
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews
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Applications : /

Sample type: cells

Review: CHD2 knockdown upregulated the expression of the Stra8 and C-kit genes and inhibited the expression of the Oct4, Plzf, Ccnb1, and Ccnd2 genes.

By Anonymous

Target Background

Function
Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis.
Gene References into Functions
  1. The genetic variant rs10269148 of STRA8 gene shows higher risk of spermatogenic impairment in the groups of abnormospermia than the controls PMID: 23320086
  2. Functional characterization of an homologous mouse gene. PMID: 18799751
  3. Observational study of gene-disease association. (HuGE Navigator) PMID: 20378615
  4. Expression restricted to testis (STRA8) PMID: 12489526
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Expressed specifically in testis and fetal ovaries.
Database Links

HGNC: 30653

OMIM: 609987

KEGG: hsa:346673

STRING: 9606.ENSP00000275764

UniGene: Hs.592279

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