STRA8 Antibody

Code CSB-PA006119
Size US$167
  • Western Blot analysis of NIH-3T3, 293 cells using Stra8 Polyclonal Antibody.
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Product Details

Uniprot No. Q7Z7C7
Target Names STRA8
Alternative Names
Stimulated by retinoic acid 8 antibody; stimulated by retinoic acid 8 homolog antibody; Stimulated by retinoic acid Gene 8 antibody; stimulated by retinoic acid gene 8 homolog antibody; Stimulated by retinoic acid gene 8 protein homolog antibody; STRA 8 antibody; STRA8 antibody; STRA8_HUMAN antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Synthesized peptide derived from the Internal region of Human Stra8.
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Isotype IgG
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form Liquid
Tested Applications WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis.
Gene References into Functions
  1. The genetic variant rs10269148 of STRA8 gene shows higher risk of spermatogenic impairment in the groups of abnormospermia than the controls PMID: 23320086
  2. Functional characterization of an homologous mouse gene. PMID: 18799751
  3. Observational study of gene-disease association. (HuGE Navigator) PMID: 20378615
  4. Expression restricted to testis (STRA8) PMID: 12489526
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Expressed specifically in testis and fetal ovaries.
Database Links

HGNC: 30653

OMIM: 609987

KEGG: hsa:346673

STRING: 9606.ENSP00000275764

UniGene: Hs.592279

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