SULT1A2 Antibody, HRP conjugated

Code CSB-PA022934LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SULT1A2 Polyclonal antibody
Uniprot No.
Target Names
SULT1A2
Alternative Names
Aryl sulfotransferase 2 antibody; Arylamine sulfotransferase antibody; HAST4 antibody; MGC142287 antibody; MGC142289 antibody; P PST antibody; P-PST 2 antibody; Phenol preferring phenol sulfotransferase 2 antibody; Phenol sulfotransferase 2 antibody; Phenol-sulfating phenol sulfotransferase 2 antibody; Phenolic metabolizing (P) form of PST antibody; ST1A2 antibody; ST1A2_HUMAN antibody; STP2 antibody; Sulfotransferase 1A2 antibody; Sulfotransferase family cytosolic 1A phenol preferring member 2 antibody; SULT1A2 antibody; Thermostable phenol sulfotransferase antibody; TSPST2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Sulfotransferase 1A2 protein (195-284AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfonation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.
Gene References into Functions
  1. Suggest SULT1A1/1A2 play a central role in furfuryl alcohol bioactivation and the formation of hemoglobin adducts. PMID: 29908303
  2. The polymorphism of SULT1A2*2 is not associated with esophageal squamous cell carcinoma risk. PMID: 26455829
  3. SULT1A2 genotype also seems to play an important role in maintaining optimal levels of both 4OH-TAM and endoxifen. PMID: 23922954
  4. resequenced the SULT1A2 and SULT1A2 genes and identified 51 variations in ethnic Koreans, including 9 that were previously unknown. Allele frequencies, haplotype structures, LD blocks, and haplotype-tagging SNPs were determined. PMID: 23358261
  5. the statistical hypothesis that SULT1A1 and SULT1A2 alleles are independently distributed was rejected; a strongly positive linkage was detected between SULT1A1*2 and SULT1A2*2 alleles in Turkey population PMID: 20936502
  6. the structures of SULT1A2 and an allozyme of SULT1A1, SULT1A1 *3, bound with 3'-phosphoadenosine 5'-phosphate at 2.4 and 2.3A resolution, respectively, were determined. PMID: 20417180
  7. SULT1A2 polymorphisms in 230 Taiwanese breast cancer patients PMID: 12373301
  8. the relationship among the polymorphisms of this enzyme and SULT1A1 in different types of cancers in Taiwanese PMID: 12469224
  9. SULT1A1*2 and SULT1A2*2 are the major allelic variants in the Korean population PMID: 16133548
  10. SULT1A1/SULT1A2 gene complex showed suggestive haplotypic association in the family-based cardiovascular disease study, with the greatest increase in risk conferred by the SULT1A2 235T allele PMID: 18259693

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Subcellular Location
Cytoplasm.
Protein Families
Sulfotransferase 1 family
Database Links

HGNC: 11454

OMIM: 601292

KEGG: hsa:6799

STRING: 9606.ENSP00000338742

UniGene: Hs.546304

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