SULT1A2 Antibody

Datasheet

Code	CSB-PA022934LA01HU
Size	US$166
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Image	IHC image of CSB-PA022934LA01HU diluted at 1:200 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. IHC image of CSB-PA022934LA01HU diluted at 1:200 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SULT1A2 Polyclonal antibody

Uniprot No.

P50226

Target Names

SULT1A2

Alternative Names

Aryl sulfotransferase 2 antibody; Arylamine sulfotransferase antibody; HAST4 antibody; MGC142287 antibody; MGC142289 antibody; P PST antibody; P-PST 2 antibody; Phenol preferring phenol sulfotransferase 2 antibody; Phenol sulfotransferase 2 antibody; Phenol-sulfating phenol sulfotransferase 2 antibody; Phenolic metabolizing (P) form of PST antibody; ST1A2 antibody; ST1A2_HUMAN antibody; STP2 antibody; Sulfotransferase 1A2 antibody; Sulfotransferase family cytosolic 1A phenol preferring member 2 antibody; SULT1A2 antibody; Thermostable phenol sulfotransferase antibody; TSPST2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Sulfotransferase 1A2 protein (195-284AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SULT1A2 Antibody (Product code: CSB-PA022934LA01HU) is Non-conjugated. For SULT1A2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA022934LB01HU	SULT1A2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA022934LC01HU	SULT1A2 Antibody, FITC conjugated
Biotin	CSB-PA022934LD01HU	SULT1A2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:200-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfonation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.

Gene References into Functions

Suggest SULT1A1/1A2 play a central role in furfuryl alcohol bioactivation and the formation of hemoglobin adducts. PMID: 29908303
The polymorphism of SULT1A2*2 is not associated with esophageal squamous cell carcinoma risk. PMID: 26455829
SULT1A2 genotype also seems to play an important role in maintaining optimal levels of both 4OH-TAM and endoxifen. PMID: 23922954
resequenced the SULT1A2 and SULT1A2 genes and identified 51 variations in ethnic Koreans, including 9 that were previously unknown. Allele frequencies, haplotype structures, LD blocks, and haplotype-tagging SNPs were determined. PMID: 23358261
the statistical hypothesis that SULT1A1 and SULT1A2 alleles are independently distributed was rejected; a strongly positive linkage was detected between SULT1A1*2 and SULT1A2*2 alleles in Turkey population PMID: 20936502
the structures of SULT1A2 and an allozyme of SULT1A1, SULT1A1 *3, bound with 3'-phosphoadenosine 5'-phosphate at 2.4 and 2.3A resolution, respectively, were determined. PMID: 20417180
SULT1A2 polymorphisms in 230 Taiwanese breast cancer patients PMID: 12373301
the relationship among the polymorphisms of this enzyme and SULT1A1 in different types of cancers in Taiwanese PMID: 12469224
SULT1A1*2 and SULT1A2*2 are the major allelic variants in the Korean population PMID: 16133548
SULT1A1/SULT1A2 gene complex showed suggestive haplotypic association in the family-based cardiovascular disease study, with the greatest increase in risk conferred by the SULT1A2 235T allele PMID: 18259693

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Subcellular Location

Cytoplasm.

Protein Families

Sulfotransferase 1 family

Database Links

HGNC: 11454

OMIM: 601292

KEGG: hsa:6799

STRING: 9606.ENSP00000338742

UniGene: Hs.546304

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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