TAAR5 Antibody

Code CSB-PA023057LA01HU
Size US$166
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Image
  • Western Blot
    Positive WB detected in: Rat brain tissue, Mouse brain tissue
    All lanes: TAAR5 antibody at 3μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 39 kDa
    Observed band size: 39 kDa

  • IHC image of CSB-PA023057LA01HU diluted at 1:600 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • Immunofluorescence staining of Hela cells with CSB-PA023057LA01HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TAAR5 Polyclonal antibody
Uniprot No.
Target Names
TAAR5
Alternative Names
TAAR5; PNR; Trace amine-associated receptor 5; TaR-5; Trace amine receptor 5; hTaar5; Putative neurotransmitter receptor
Raised in
Rabbit
Species Reactivity
Human, Rat, Mouse
Immunogen
Recombinant Human Trace amine-associated receptor 5 protein (1-34AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TAAR5 Antibody (Product code: CSB-PA023057LA01HU) is Non-conjugated. For TAAR5 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA023057LB01HU TAAR5 Antibody, HRP conjugated ELISA
FITC CSB-PA023057LC01HU TAAR5 Antibody, FITC conjugated
Biotin CSB-PA023057LD01HU TAAR5 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:500-1:1000
IF 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Olfactory receptor specific for trimethylamine, a trace amine. Also activated at lower level by dimethylethylamine. Trimethylamine is a bacterial metabolite found in some animal odors, and to humans it is a repulsive odor associated with bad breath and spoiled food. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase.
Gene References into Functions
  1. The murine and human TAAR5 (hTAAR5) display significant basal activity in the Gq/11 pathway. PMID: 25706283
  2. Human trace amine-associated receptor TAAR5 can be activated by trimethylamine. PMID: 23393561
  3. Previous studies reported TAAR expression in brain. This paper found TAAR expression only in olfactory epithelial cells and that each TAAR detects a unique set of amine ligands. TAARs seem to function as a family of chemosensory receptors for amines. PMID: 16878137
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family
Tissue Specificity
Expressed almost exclusively in skeletal muscle and selected areas of the brain, such amygdala, hippocampus, caudate nucleus, thalamus and hypothalamus. Weak expression is also find in substantia nigra.
Database Links

HGNC: 30236

OMIM: 607405

KEGG: hsa:9038

STRING: 9606.ENSP00000258034

UniGene: Hs.248198

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