TAF1A Antibody

Code CSB-PA070201
Size US$100
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Product Details

Uniprot No.
Target Names
TAF1A
Alternative Names
MGC:17061 antibody; RAFI48 antibody; RNA polymerase I-specific TBP-associated factor 48 kDa antibody; SL1 48kD subunit antibody; SL1 antibody; Taf1a antibody; TAF1A_HUMAN antibody; TAFI48 antibody; TATA box binding protein (TBP) associated factor RNA polymerase I, A 48kDa antibody; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A antibody; TATA box binding protein associated factor 1A antibody; TATA box binding protein associated factor RNA polymerase I subunit A antibody; TATA box-binding protein-associated factor 1A antibody; TATA box-binding protein-associated factor RNA polymerase I subunit A antibody; TBP associated factor RNA polymerase I 48 kDa antibody; TBP-associated factor 1A antibody; Transcription factor SL1 antibody; Transcription initiation factor SL1/TIF-IB subunit A antibody
Raised in
Rabbit
Species Reactivity
Human,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human TAF I p48.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
Gene References into Functions
  1. This study identifies the first nuclear import sequence within the TBP-Associated Factor subunits of Selectivity Factor 1. PMID: 15113842
  2. The authors demonstrate the interaction of both RNA polymerase I and III with hepatitis delta virus RNA, both in vitro and in human cells. PMID: 19246067
Subcellular Location
Nucleus.
Database Links

HGNC: 11532

OMIM: 604903

KEGG: hsa:9015

STRING: 9606.ENSP00000327072

UniGene: Hs.153088

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