TAF1A Antibody

Code CSB-PA949229
Size US$297
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  • Western blot analysis of extracts from HeLa cells, using TAF1A antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TAF1A Polyclonal antibody
Uniprot No.
Target Names
TAF1A
Alternative Names
MGC:17061 antibody; RAFI48 antibody; RNA polymerase I-specific TBP-associated factor 48 kDa antibody; SL1 48kD subunit antibody; SL1 antibody; Taf1a antibody; TAF1A_HUMAN antibody; TAFI48 antibody; TATA box binding protein (TBP) associated factor RNA polymerase I, A 48kDa antibody; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A antibody; TATA box binding protein associated factor 1A antibody; TATA box binding protein associated factor RNA polymerase I subunit A antibody; TATA box-binding protein-associated factor 1A antibody; TATA box-binding protein-associated factor RNA polymerase I subunit A antibody; TBP associated factor RNA polymerase I 48 kDa antibody; TBP-associated factor 1A antibody; Transcription factor SL1 antibody; Transcription initiation factor SL1/TIF-IB subunit A antibody
Raised in
Rabbit
Species Reactivity
Human,Rat
Immunogen
Synthesized peptide derived from internal of Human TAF1A.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
Gene References into Functions
  1. This study identifies the first nuclear import sequence within the TBP-Associated Factor subunits of Selectivity Factor 1. PMID: 15113842
  2. The authors demonstrate the interaction of both RNA polymerase I and III with hepatitis delta virus RNA, both in vitro and in human cells. PMID: 19246067
Subcellular Location
Nucleus.
Database Links

HGNC: 11532

OMIM: 604903

KEGG: hsa:9015

STRING: 9606.ENSP00000327072

UniGene: Hs.153088

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