TARS2 Antibody

Code CSB-PA023132LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA023132LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA023132LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TARS2 Polyclonal antibody
Uniprot No.
Target Names
TARS2
Alternative Names
TARS2 antibody; TARSL1 antibody; Threonine--tRNA ligase antibody; mitochondrial antibody; EC 6.1.1.3 antibody; Threonyl-tRNA synthetase antibody; ThrRS antibody; Threonyl-tRNA synthetase-like 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Threonine--tRNA ligase, mitochondrial protein (369-718AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TARS2 Antibody (Product code: CSB-PA023132LA01HU) is Non-conjugated. For TARS2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA023132LB01HU TARS2 Antibody, HRP conjugated ELISA
FITC CSB-PA023132LC01HU TARS2 Antibody, FITC conjugated
Biotin CSB-PA023132LD01HU TARS2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain.
Gene References into Functions
  1. Identification of a TARS2 splicing variant in several human cell lines, which encodes a hmtThrRS derivative lacking a peptide covering a portion of both the editing and the aminoacylation domains. PMID: 26811336
  2. TARS2 mutations caused fatal mitochondrial encephalomyopathy in two siblings. PMID: 24827421
Involvement in disease
Combined oxidative phosphorylation deficiency 21 (COXPD21)
Subcellular Location
Mitochondrion matrix.
Protein Families
Class-II aminoacyl-tRNA synthetase family
Database Links

HGNC: 30740

OMIM: 612805

KEGG: hsa:80222

STRING: 9606.ENSP00000358060

UniGene: Hs.288974

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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