TARS2 Antibody

Datasheet

Code	CSB-PA023132LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA023132LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA023132LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TARS2 Polyclonal antibody

Uniprot No.

Q9BW92

Target Names

TARS2

Alternative Names

TARS2 antibody; TARSL1 antibody; Threonine--tRNA ligase antibody; mitochondrial antibody; EC 6.1.1.3 antibody; Threonyl-tRNA synthetase antibody; ThrRS antibody; Threonyl-tRNA synthetase-like 1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Threonine--tRNA ligase, mitochondrial protein (369-718AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TARS2 Antibody (Product code: CSB-PA023132LA01HU) is Non-conjugated. For TARS2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA023132LB01HU	TARS2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA023132LC01HU	TARS2 Antibody, FITC conjugated
Biotin	CSB-PA023132LD01HU	TARS2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain.

Gene References into Functions

Identification of a TARS2 splicing variant in several human cell lines, which encodes a hmtThrRS derivative lacking a peptide covering a portion of both the editing and the aminoacylation domains. PMID: 26811336
TARS2 mutations caused fatal mitochondrial encephalomyopathy in two siblings. PMID: 24827421

Involvement in disease

Combined oxidative phosphorylation deficiency 21 (COXPD21)

Subcellular Location

Mitochondrion matrix.

Protein Families

Class-II aminoacyl-tRNA synthetase family

Database Links

HGNC: 30740

OMIM: 612805

KEGG: hsa:80222

STRING: 9606.ENSP00000358060

UniGene: Hs.288974

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Virus Infection Target Therapy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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