TBC1D15 Antibody, FITC conjugated

Code CSB-PA823452LC01HU
Size US$166
Order now
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TBC1D15 Polyclonal antibody
Uniprot No.
Target Names
TBC1D15
Alternative Names
DKFZp686M1379 antibody; DKFZp761D0223 antibody; FLJ12085 antibody; FLJ33191 antibody; GAP for RAB7 antibody; GTPase-activating protein RAB7 antibody; RAB7 GAP antibody; Rab7-GAP antibody; TBC1 domain family member 15 antibody; TBC15_HUMAN antibody; Tbc1d15 antibody; Tre 2 budding uninhibited by benzimidazole cell division cycle 16 domain; domain family member 15 antibody; Tre2/Bub2/Cdc16 domain family member 15 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human TBC1 domain family member 15 protein (283-404AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Acts as a GTPase activating protein for RAB7A. Does not act on RAB4, RAB5 or RAB6.
Gene References into Functions
  1. Report provides evidence for a new function of TBC1D15 in the control of GLUT4 vesicles translocation through regulating Rab7 activity. Glucose uptake was greatly reduced when TBC1D15 was knocked out. PMID: 30316925
  2. Demonstrate that TBC1D15 and TBC1D17 mediate proper autophagic encapsulation of mitochondria by regulating Rab7 activity at the interface between mitochondria and isolation membranes. PMID: 24569479
  3. TBC1D15 is required for the accumulation of RhoA. PMID: 24337944
  4. Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology. PMID: 23077178
  5. although only TBC1D15/Rab7-GAP altered Rab7-GTP levels, both Rab7-GAP and mVps39 regulate lysosomal morphology and play a role in maintaining growth factor dependence PMID: 20363736
  6. This paper primarily describes mouse TBC1D15 but also reports the primary structure of human TBC1D15. PMID: 16055087

Show More

Hide All

Subcellular Location
Cytoplasm.
Database Links

HGNC: 25694

OMIM: 612662

KEGG: hsa:64786

STRING: 9606.ENSP00000448182

UniGene: Hs.284630

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
webinars: DT3C facilitates antibody internalization X
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*