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TBKBP1 Antibody, FITC conjugated

Datasheet
Code CSB-PA023233LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TBKBP1 Polyclonal antibody
Uniprot No.
A7MCY6
Target Names
TBKBP1
Alternative Names
KIAA0775 antibody; ProSAPiP2 antibody; SINTBAD antibody; TANK binding kinase 1 binding protein 1 antibody; TANK-binding kinase 1-binding protein 1 antibody; TBK1 binding protein 1 antibody; TBK1-binding protein 1 antibody; TBKB1_HUMAN antibody; Tbkbp1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human TANK-binding kinase 1-binding protein 1 protein (327-427AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.
Gene References into Functions
  1. The two selected single nucleotide polymorphisms (SNPs) in TBKBP1 show no relationship with the clinical outcomes. None of the 12 SNPs is related to mSASSS. PMID: 25494292
  2. TBKBP1 is associated with the severity of ankylosing spondylitis in the Chinese Han population PMID: 23637848
  3. Studies show that three proteins expressed in HEK-293T cells (NAP1, TANK and TBKBP1) interact with TBK1. PMID: 23286385
  4. results suggest that efficient signal transduction upon viral infection requires SINTBAD, TANK and NAP1 because they link TBK1 and IKKi to virus-activated signalling cascades PMID: 17568778
Tissue Specificity
Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
Database Links

HGNC: 30140

OMIM: 608476

KEGG: hsa:9755

STRING: 9606.ENSP00000354777

UniGene: Hs.94790

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