TCF19 Antibody

Code CSB-PA023295LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: HL60 whole cell lysate
    All lanes: TCF19 antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 38 kDa
    Observed band size: 38 kDa
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TCF19 Polyclonal antibody
Uniprot No.
Target Names
TCF19
Alternative Names
Transcription factor 19 (TCF-19) (Transcription factor SC1), TCF19, SC1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transcription factor 19 protein (12-250aa)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TCF19 Antibody (Product code: CSB-PA023295LA01HU) is Non-conjugated. For TCF19 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA023295LB01HU TCF19 Antibody, HRP conjugated ELISA
FITC CSB-PA023295LC01HU TCF19 Antibody, FITC conjugated
Biotin CSB-PA023295LD01HU TCF19 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression.
Gene References into Functions
  1. Data suggest TCF19 interacts with histone 3 lysine 4 trimethylation through its plant homeodomain finger; TCF19 expression appears to regulate gluconeogenesis in hepatocytes; TCF19 interacts with CHD4 causing NuRD complex recruitment to gene promoters of enzymes involved in gluconeogenesis. (TCF19 = transcription factor 19; CHD4 = chromodomain helicase DNA binding protein 4; NuRD = nucleosome-remodeling-deacetylase) PMID: 29042441
  2. Genome association studies identified TCF19 as a new risk-associated loci for chronic hepatitis B on the HLA region of chromosome 6. PMID: 23760081
  3. Data shows increased apoptosis and susceptibility to endoplasmic reticulum (ER) stress after Tcf19 knockdown. PMID: 23860123
  4. Knockdown of Tcf19 reduces proliferation and increases apoptosis. Tcf19 is found in pancreatic islets in mouse and human. PMID: 23860123
  5. A linkage disequilibrium analysis established TCF19, POU5F1, CCHCR1 and PSORS1C1 as potential causal genes for the type 1 diabetes. PMID: 21076979

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Subcellular Location
Nucleus.
Database Links

HGNC: 11629

OMIM: 600912

KEGG: hsa:6941

STRING: 9606.ENSP00000365431

UniGene: Hs.584807

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