TFAP2E Antibody, Biotin conjugated

Datasheet
Code CSB-PA761516LD01HU
Size US$299
Uniprot No. Q6VUC0
Immunogen Recombinant Human Transcription factor AP-2-epsilon protein (66-175AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation (By similarity).
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Transcription factor AP-2-epsilon (AP2-epsilon) (Activating enhancer-binding protein 2-epsilon), TFAP2E
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Epigenetics and Nuclear Signaling
Target Names TFAP2E
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation (By similarity).
Subcellular Location Nucleus
Protein Families AP-2 family
Tissue Specificity Expressed in skin, primary keratinocytes, immortalized keratinocytes, and HeLa cell line.
Database Links

HGNC: 30774

OMIM: 614428

KEGG: hsa:339488

STRING: 9606.ENSP00000362332

UniGene: Hs.567844

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